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Western Medicine Tablets Phenoxymethylpenicillin Tablets Bp 400,000IU For Bacterial Treatment

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Western Medicine Tablets Phenoxymethylpenicillin Tablets Bp 400,000IU For Bacterial Treatment

Brand Name : Uni-pharma
Model Number : BP 400,000IU
Certification : GMP
Place of Origin : China
MOQ : 6000000tables
Price : USD 1.55/Box
Payment Terms : L/C, D/A, D/P, T/T
Delivery Time : After packaging confirmed 30 days
Packaging Details : 10 tablets/tube* 12 tubes/box
Applications : Internal Medicine
Usage method : For oral administration
Applicable people : Adults/Children
Form : Solid
Shape : Tablet
Type : Biological Products
Pharmaceutical methods : Chemical Synthesis
Specification : 400,000IU
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Western Medicine PHENOXYMETHYLPENICILLIN TABLETS BP 400,000IU (an antibiotic useful for the treatment of bacterial)


Each tablet contains:

Phenoxymethylpenicillin Potassium BP

equivalent to

Phenoxymethypenicillin BP 400,000IU


Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. Specifically it is used for the treatment of strep throat, otitis media, and cellulitis. It is also used to prevent rheumatic fever and to prevent infections follow removal of the spleen. It is given by mouth.

Side effects include diarrhea, nausea, and allergic reactions including anaphylaxis. It is not recommended in those with a history of penicillin allergy. It is relatively safe for use during pregnancy. It is in the penicillin and beta lactam family of medications. It usually results inbacterial death.

Phenoxymethylpenicillin was first made in 1948. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. It is available as a generic medication. The wholesale cost in the developing world is about 0.05 to 0.96 USD per day. In the United States a course of treatment costs less than 25 USD.


[Indications]

Mild and moderate infection of penicillin V potassium tablets for penicillin sensitive strain induced, including Streptococcus caused by tonsillitis, pharyngitis, scarlet fever, erysipelas; pneumococcal pneumonia, caused by bronchitis, sinusitis and otitis media, sensitive Staphylococcus aureus caused by skin and soft tissue infection. Penicillin V potassium tablets may also be used for the prevention of infection and the use of drugs for the prevention of recurrent rheumatic fever and infectious endocarditis.


[Note]

1 each patient before taking penicillin V potassium tablets, penicillin skin test must be carried out.

2 of cephalosporin allergy and disease history of allergic asthma, eczema, hayfever, urticaria and other caution.

3 penicillin V potassium tablets and other penicillin drugs have cross allergic. If there is an allergic reaction, it should immediately stop penicillin V potassium tablets, and take appropriate measures.

4 patients with impaired renal function should adjust the dose or dosing interval according to the plasma creatinine clearance rate.

5 treatment of streptococcal infection need to be treated for 10 days, after the end of treatment should be used for bacterial culture, to determine whether the removal of streptococcus.

6 patients with suspected syphilis associated with syphilis should be examined by a dark field before the use of penicillin V potassium tablets and, at least within 4 months, a monthly serum test.

7 long term or large doses of penicillin V potassium tablets, should regularly check the liver, kidney, hematopoietic system function and detection of serum potassium or sodium.

8 The interference of the laboratory index:

(1) copper sulfate method of urine test may be a false positive, but glucose test method is not affected;

(2) the serum alanine aminotransferase or aspartate aminotransferase determination value increased.


[Usage and Dosage]


adult1-1 1/2 tablets every 6 hours
Children (above 1 year)1/2 tablets every 6 hours or as directed by the Physician


[Oral administration]
Adult streptococcal infection: a 125 ~ 250mg, every 6 ~ 8 hours 1 times, treatment for 10 days.
Pneumococcal infection: a 250 ~ 500mg, 1 times every 6 hours, at least 2 days after the treatment to fever.
Staphylococcal infection, spirochete infection (Vincent's angina): spirochete infection (Vincent's angina): a 250~500mg, every 6 ~ 8 hours
Prevention of recurrence of rheumatic fever: a 250mg, 2 times a day.
Prevention of endocarditis: in the tooth extraction or upper respiratory tract surgery 1 hours before taking penicillin V potassium tablets 2G, after 6 hours and then take 1g (27kg below the child dose halved).
Children according to weight, once 2.5~9.3mg/kg, every 4 hours 1 times; or a 3.75~14 mg/kg, every 6 hours 1 times; or a 5~18.7 mg/kg, every 8 hours.


[Taboo]

Penicillin skin test positive reaction, penicillin V potassium tablets and other penicillin allergy and infectious mononucleosis patients.


[Pregnant Women and Lactating Women Medication Notes]

1 penicillin V potassium tablets can enter the fetus through the placenta, so pregnant women with caution.

2 penicillin V potassium tablets can be secreted into the milk, the baby may cause sensitization and cause


[Elderly Medication Note]

Elderly patients should be adjusted according to the renal function of the drug dose or interval.


[Adverse Reactions]

1 common nausea, vomiting, abdominal discomfort, diarrhea and other gastrointestinal reaction and black tongue.

2 allergic reactions: skin rash (especially in patients with infectious mononucleosis), urticaria and other serum sickness like reactions, laryngeal edema, heat and other drugs, such as eosinophilia.

3: double infection or a large number of long-term use of penicillin V potassium tablets can cause penicillin resistant Staphylococcus aureus, gram negative bacilli or Candida albicans infection (brown or black fur).

4 rare hemolytic anemia, transient increase of serum aminotransferase, white blood cells, thrombocytopenia, neurotoxicity and nephrotoxicity.


[Medical uses]

Specific indications for phenoxymethylpenicillin include:

Infections caused by Streptococcus pyogenes
Tonsillitis
Pharyngitis
Skin infections
Anthrax (mild uncomplicated infections)
Lyme disease (early stage in pregnant women or young children)
Rheumatic fever (primary and secondary prophylaxis)
Streptococcal skin infections
Spleen disorders (pneumococcal infection prophylaxis)
Initial treatment for Dental Abscesses
Moderate-to-severe gingivitis (with metronidazole)
Avulsion injuries of teeth (as an alternative to tetracycline)
Blood infection prophylaxis in children with sickle cell disease.

Penicillin V is sometimes used in the treatment of odontogenic infections.

It is less active than benzylpenicillin (penicillin G) against Gram-negative bacteria.Phenoxymethylpenicillin has a range of antimicrobial activity against Gram-positive bacteria that is similar to that of benzylpenicillin and a similar mode of action, but it is substantially less active than benzylpenicillin against Gram-negative bacteria.

Phenoxymethylpenicillin is more acid-stable than benzylpenicillin, which allows it to be given orally.

Phenoxymethylpenicillin is usually used only for the treatment of mild to moderate infections, and not for severe or deep-seated infections sinceabsorption can be unpredictable. Except for the treatment or prevention of infection with Streptococcus pyogenes (which is uniformly sensitive to penicillin), therapy should be guided by bacteriological studies (including sensitivity tests) and by clinical response.People treated initially withparenteral benzylpenicillin may continue treatment with phenoxymethylpenicillin by mouth once a satisfactory response has been obtained.

It is not active against beta-lactamase-producing bacteria, which include many strains of Staphylococci.


[Adverse effects]
Further information: Penicillin drug reaction

Phenoxymethylpenicillin is usually well tolerated but may occasionally cause transient nausea, vomiting, epigastric distress, diarrhea, constipation, acidic smell to urine and black hairy tongue. A previous hypersensitivity reaction to any penicillin is a contraindication.


[Mechanism of action]

It exerts a bactericidal action against penicillin-sensitive microorganisms during the stage of active multiplication. It acts by inhibiting thebiosynthesis of cell-wall peptidoglycan.


[Storage]

Store in a cool & dry palce.

Keep out of the reach of children



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